Laitakari K
Department of Otolaryngology, University of Oulu, Finland.
Clin Otolaryngol Allied Sci. 1990 Dec;15(6):545-8. doi: 10.1111/j.1365-2273.1990.tb00796.x.
From 1982 to 1987, 20 patients with disabling attacks of vertigo and severe hearing loss due to unilateral Ménière's disease were treated with local intratympanic gentamycin. In 18 patients control of vertiginous attacks was achieved. Hearing deteriorated in 8 patients. In spite of complete control of attacks a disabling ablation type of unsteadiness and dizziness affected 7 patients. Two patients required additional treatment after 5-8 months remission. Intratympanic gentamycin seems to be a less useful method of treating severe unilateral Ménière's disease than previously stated. It is, however, a possible alternative to surgical labyrinthectomy with a fair chance of residual hearing preservation.
1982年至1987年，对20例因单侧梅尼埃病导致眩晕发作致残且听力严重丧失的患者采用鼓室内注射庆大霉素进行治疗。18例患者的眩晕发作得到控制。8例患者听力下降。尽管发作得到了完全控制，但仍有7例患者出现了致残性的共济失调型不稳和头晕。2例患者在缓解5 - 8个月后需要额外治疗。鼓室内注射庆大霉素治疗重度单侧梅尼埃病似乎不像之前所说的那么有效。然而，它是手术性迷路切除术的一种可能替代方法，有相当大的机会保留残余听力。
