Department of Otolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Clin Otolaryngol. 2010 Aug;35(4):300-6. doi: 10.1111/j.1749-4486.2010.02155.x.
The aim of this study was to compare the surgical outcomes of endoscopic sinus surgery in two patient groups: adults younger than 65 years of age and adults aged 65 years or older.
A retrospective study.
This study was conducted at an academic tertiary referral centre.
One hundred and eighty consecutive older patients (> or =65 years), and 180 adult patients (>15, <65 years) with chronic rhinosinusitis who underwent endoscopic sinus surgery under local anaesthesia between 1997 and 2007 were enrolled in this study.
Recurrence and complication rates were analyzed. Data were analyzed using the Mann-Whitney test, Fisher's Exact test, the Pearson Chi-Square test, and univariate and multivariate logistic regression. P < 0.05 was considered statistically significant.
When looked at without control for other factors the surgical complication rates were higher in the older group patients (31%) compared with the younger patients (11%). However, multivariate logistic regression analysis showed that preoperative duration of symptoms, length of follow-up, and diabetes mellitus were positively correlated with complications. In this analysis, the older patients, once controlled for these factors, were less likely to have complications. Regarding recurrence, in multivariate analysis there was no difference between the older and the younger group with preoperative duration and length of postoperative follow-up having a small effect.
Comorbidity especially diabetes mellitus and duration of the condition should be the factors considered preoperatively to predict the likely hood of complications rather than whether the patient is younger or older that 65 years of age.
本研究旨在比较内镜鼻窦手术在两组患者中的手术结果:年龄小于 65 岁的成年人和年龄等于或大于 65 岁的成年人。
回顾性研究。
本研究在一家学术性三级转诊中心进行。
180 例连续的老年患者(>或=65 岁)和 180 例成人患者(>15 岁,<65 岁),他们于 1997 年至 2007 年间在局部麻醉下接受了内镜鼻窦手术。
复发和并发症发生率进行分析。使用 Mann-Whitney 检验、Fisher 确切检验、Pearson Chi-Square 检验以及单变量和多变量逻辑回归分析数据。P<0.05 被认为具有统计学意义。
如果不考虑其他因素,老年组患者的手术并发症发生率(31%)高于年轻患者(11%)。然而,多变量逻辑回归分析表明,术前症状持续时间、随访时间长度和糖尿病与并发症呈正相关。在该分析中,一旦控制了这些因素,老年患者发生并发症的可能性较小。关于复发,多变量分析显示,老年组和年轻组之间没有差异,术前持续时间和术后随访时间长度的影响较小。
应在术前考虑合并症,特别是糖尿病和疾病持续时间,以预测并发症的可能性,而不是患者是否年龄大于或等于 65 岁。