Solak Y, Atalay H, Nar A, Ozbek O, Turkmen K, Erekul S, Turk S
Department of Nephrology, Selcuk University, Meram School of Medicine, Meram, Konya, Turkey.
Transpl Infect Dis. 2011 Apr;13(2):178-81. doi: 10.1111/j.1399-3062.2010.00557.x. Epub 2010 Aug 25.
Fungal pathogens are increasingly encountered after renal transplantation. Aspergillus causes significant morbidity and mortality in transplant patients. Fungal thyroiditis is a rare occurrence owing to unique features of the thyroid gland. Most cases are caused by Aspergillus species and have been described in immunocompromised patients. Presentation may be identical with that of subacute thyroiditis, in which hyperthyroidism features and painful thyroid are the prominent findings. Diagnosis can be ascertained by fine-needle aspiration of thyroid showing branching hyphae of Aspergillus. We describe a renal transplant patient who developed Aspergillus thyroiditis as part of a disseminated infection successfully treated with voriconazole.
肾移植后越来越多地遇到真菌病原体。曲霉菌在移植患者中可导致严重的发病率和死亡率。由于甲状腺的独特特征，真菌性甲状腺炎很少见。大多数病例由曲霉菌属引起，且已在免疫功能低下的患者中有所描述。其表现可能与亚急性甲状腺炎相同，其中甲状腺功能亢进特征和甲状腺疼痛是突出表现。通过甲状腺细针穿刺显示曲霉菌的分支菌丝可确诊。我们描述了一名肾移植患者，其发生了曲霉菌性甲状腺炎，作为播散性感染的一部分，用伏立康唑成功治疗。
