Santiago Mónica, Martinez José Hernán, Palermo Coromoto, Figueroa Carlos, Torres Oberto, Trinidad Rafael, Gonzalez Eva, Miranda Maria de Lourdes, Garcia Miosotis, Villamarzo Guillermo
Department of Endocrinology, Metabolism, and Diabetes, San Juan City Hospital, Puerto Rico.
Case Rep Endocrinol. 2013;2013:290843. doi: 10.1155/2013/290843. Epub 2013 Jul 9.
We describe a 20-year-old man diagnosed with a myelodysplastic syndrome (MDS), admitted to our hospital due to pancytopenia and fever of undetermined origin after myelosuppression with chemotherapy. Disseminated aspergillosis (DIA) was suspected when he developed skin and lung involvement. A rapidly growing mass was detected on the left neck area, during hospitalization. A thyroid ultrasound reported a 3.7 × 2.5 × 2.9 cm oval heterogeneous structure, suggestive of an abscess versus a hematoma. Fine needle aspiration of the thyroid revealed invasion of aspergillosis. Fungal thyroiditis is a rare occurrence. Thyroid fungal infection is difficult to diagnose; for this reason it is rarely diagnosed antemortem. To our knowledge, this is the 10th case reported in the literature in an adult where the diagnosis of fungal invasion to the thyroid was able to be corroborated antemortem by fine needle aspiration biopsy.
我们描述了一名20岁被诊断为骨髓增生异常综合征（MDS）的男性，在接受化疗导致骨髓抑制后，因全血细胞减少和不明原因发热入住我院。当他出现皮肤和肺部受累时，怀疑患有播散性曲霉病（DIA）。住院期间，在左侧颈部区域发现一个迅速增大的肿块。甲状腺超声报告显示一个3.7×2.5×2.9厘米的椭圆形不均匀结构，提示脓肿或血肿。甲状腺细针穿刺显示曲霉病浸润。真菌性甲状腺炎很少见。甲状腺真菌感染难以诊断；因此很少能在生前确诊。据我们所知，这是文献中报道的第10例成人患者，通过细针穿刺活检能够在生前证实甲状腺真菌浸润的诊断。
