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PharmGKB summary: cytochrome P450, family 2, subfamily J, polypeptide 2: CYP2J2.

作者信息

Berlin Dorit S, Sangkuhl Katrin, Klein Teri E, Altman Russ B

机构信息

Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA.

出版信息

Pharmacogenet Genomics. 2011 May;21(5):308-11. doi: 10.1097/FPC.0b013e32833d1011.

DOI:10.1097/FPC.0b013e32833d1011
PMID:20739908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3086341/
Abstract
摘要

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本文引用的文献

1
Identification of novel substrates for human cytochrome P450 2J2.鉴定人细胞色素 P450 2J2 的新型底物。
Drug Metab Dispos. 2010 Feb;38(2):347-56. doi: 10.1124/dmd.109.030270. Epub 2009 Nov 18.
2
The common functional polymorphism -50G>T of the CYP2J2 gene is not associated with ischemic coronary and cerebrovascular events in an urban-based sample of Swedes.CYP2J2 基因的常见功能多态性-50G>T 与瑞典城市人群的缺血性冠状动脉和脑血管事件无关。
J Hypertens. 2010 Feb;28(2):294-9. doi: 10.1097/HJH.0b013e328333097e.
3
The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.环氧合酶 CYP2J2 在体外和体内均可激活核受体 PPARα。
PLoS One. 2009 Oct 12;4(10):e7421. doi: 10.1371/journal.pone.0007421.
4
Expression of cytochrome P450 arachidonic acid epoxygenase 2J2 in human tumor tissues and cell lines.细胞色素P450花生四烯酸环氧化酶2J2在人肿瘤组织和细胞系中的表达。
Ai Zheng. 2009 Feb;28(2):93-6. Epub 2009 Feb 23.
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Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity.CYP2J2的过表达可提供针对阿霉素诱导的心脏毒性的保护作用。
Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H37-46. doi: 10.1152/ajpheart.00983.2008. Epub 2009 May 8.
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J Mol Cell Cardiol. 2009 Jan;46(1):67-74. doi: 10.1016/j.yjmcc.2008.09.711. Epub 2008 Oct 10.
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