顺铂联合多西他赛化疗治疗原发灶不明的胸段淋巴结转移癌——3例经验
Cisplatin plus Docetaxel Chemotherapy for Thoracic Lymph Node Metastasis from Cancer of Unknown Primary - Experience of Three Cases.
作者信息
Kobayashi Takashi, Koizumi Tomonobu, Kitaguchi Akihiro, Hatayama Orie, Tsushima Kenji, Urushihata Kazuhisa, Yamamoto Hiroshi, Hanaoka Masayuki, Kubo Keishi, Honda Takayuki, Oguchi Kazuhiro
机构信息
First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
出版信息
Case Rep Oncol. 2009 May 15;2(2):84-91. doi: 10.1159/000217136.
The optimal chemotherapeutic regimen for cancer of unknown primary (CUP) remains uncertain. We encountered 3 cases with CUP who presented with thoracic lymph node metastasis. Detailed physical examination and diagnostic tests, including laboratory investigations, bronchoscopy, upper and lower gastrointestinal studies, computed tomography of the head, neck, abdomen and pelvis and (18)F-fluorodeoxyglucose positron emission tomography, failed to identify the primary site in these cases. The patients were treated with the cisplatin plus docetaxel chemotherapy regimen. Concomitant thoracic radiotherapy was conducted in one patient and surgical resection in another. All patients showed good response to the chemotherapy and achieved long-term disease-free survival.
原发灶不明癌（CUP）的最佳化疗方案仍不确定。我们遇到3例表现为胸段淋巴结转移的CUP患者。详细的体格检查和诊断性检查，包括实验室检查、支气管镜检查、上消化道和下消化道检查、头部、颈部、腹部和骨盆的计算机断层扫描以及（18）F-氟脱氧葡萄糖正电子发射断层扫描，均未能在这些病例中确定原发部位。这些患者接受了顺铂加多西他赛化疗方案治疗。1例患者接受了同步胸段放疗，另1例接受了手术切除。所有患者对化疗均表现出良好反应，并实现了长期无病生存。
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