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全关节置换术中金属磨损颗粒的纳米毒理学：当前概念综述

Nanotoxicology of metal wear particles in total joint arthroplasty: a review of current concepts.

作者信息

Billi Fabrizio, Campbell Pat

机构信息

The J. Vernon Luck Sr., M.D. Orthopaedic Research Center, Los Angeles Orthopaedic Hospital UCLA, Los Angeles, CA 90007, USA.

出版信息

J Appl Biomater Biomech. 2010 Jan-Apr;8(1):1-6.

PMID:20740415
Abstract

Metal-on-metal (M-M) joint replacement has raised concerns about the long-term effects of metal wear debris and corrosion products. This review summarizes the current concepts in biological reactivity to metal wear particles, ions, and corrosion products. Attention is focused on Co-Cr-Mo alloy since it is the most diffused and discussed material in arthroplasty.

摘要

金属对金属（M-M）关节置换引发了人们对金属磨损碎屑和腐蚀产物长期影响的担忧。本综述总结了目前关于对金属磨损颗粒、离子和腐蚀产物生物反应性的概念。重点关注钴铬钼合金，因为它是关节置换术中应用最广泛且讨论最多的材料。

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