Goldfarb D, Gedalia A
Dept. of Pediatrics A, Soroka Medical Center, Beer Sheba.
Harefuah. 1990 Dec 16;119(12):425-7.
Acute disseminated staphylococcal disease may develop in previously healthy children below the age of 15 years. It progresses rapidly and may cause death in a significant number. The diagnostic criteria are infection in 2 or more anatomical sites and isolation of a coagulase-positive Staphylococcus aureus from the blood or from a site of infection. We present an 11.5-year-old boy with disseminated staphylococcal disease with evidence of cellulitis, osteomyelitis and endocarditis. He developed intracranial hemorrhage as a complication and survived, but with mild residual hemiparesis. Nervous system involvement, such as meningitis and brain abscess, have been described in this particularly severe disease. This is the only known report of intracranial hemorrhage as a complication of the disease.
急性播散性葡萄球菌病可能发生在15岁以下先前健康的儿童中。病情进展迅速，可能导致相当数量的儿童死亡。诊断标准为2个或更多解剖部位感染，且从血液或感染部位分离出凝固酶阳性金黄色葡萄球菌。我们报告一名11.5岁患有播散性葡萄球菌病的男孩，有蜂窝织炎、骨髓炎和心内膜炎的证据。他出现颅内出血作为并发症并存活下来，但有轻度残留偏瘫。在这种特别严重的疾病中，曾有神经系统受累的描述，如脑膜炎和脑脓肿。这是该疾病并发颅内出血的唯一已知报告。
