Bagley F H, Walsh J W, Cady B, Salzman F A, Oberfield R A, Pazianos A G
Cancer. 1978 Jun;41(6):2154-7. doi: 10.1002/1097-0142(197806)41:6<2154::aid-cncr2820410612>3.0.co;2-#.
A retrospective study was performed of 18 women in whom ipsilateral brachial plexus neuropathy developed after treatment for carcinoma of the breast. In the absence of metastatic tumor elsewhere, the only distinguishing feature between carcinomatous neuropathy and radiation-induced neuropathy was the symptom-free interval after mastectomy and radiation therapy. Women with an interval of less than a year have radiation-induced neuropathy. Brachial plexus exploration in difficult diagnostic situations will permit early treatment and avoid debilitating loss of function. Brachial plexus exploration for biopsy is safe and free of complications if performed carefully. Treatment of carcinomatous neuropathy is most likely to succeed if the tumor is hormonally sensitive, but radiotherapy may also be effective. Treatment of radiation-induced neuropathy remains largely ineffective.
对18例乳腺癌治疗后发生同侧臂丛神经病变的女性进行了一项回顾性研究。在无其他部位转移瘤的情况下，癌性神经病变与放射性神经病变之间唯一的区别特征是乳房切除和放射治疗后的无症状间隔期。间隔期少于一年的女性患有放射性神经病变。在诊断困难的情况下进行臂丛神经探查可实现早期治疗并避免功能的衰弱性丧失。如果操作仔细，用于活检的臂丛神经探查是安全且无并发症的。如果肿瘤对激素敏感，癌性神经病变的治疗最有可能成功，但放射治疗也可能有效。放射性神经病变的治疗在很大程度上仍然无效。
