Abel E L
Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
Growth Dev Aging. 1990 Fall;54(3):125-9.
In adult males, undernutrition is associated with altered spermatogenesis. The present study was performed to evaluate the possible role of paternal undernutrition on growth and development of rat offspring and to compare those effects with undernutrition in pregnant animals. Male rats were fed 100%, 80% or 60% of their ad lib food intake for eight weeks and were then bred to untreated females. Pregnant rats were mated with untreated males and received their food allotments throughout pregnancy. Although male body weights and rate of successful matings were decreased by paternal undernutrition, offspring litter size, birth weights, and weights at 21 days were not significantly altered. By contrast, maternal undernutrition was associated with decreased maternal weight gain, lower offspring birth weights and body weights at weaning.
在成年雄性中，营养不足与精子发生改变有关。本研究旨在评估父本营养不足对大鼠后代生长发育的可能作用，并将这些影响与怀孕动物的营养不足进行比较。雄性大鼠连续八周分别给予其自由采食量的100%、80%或60%的食物，然后与未处理的雌性大鼠交配。怀孕大鼠与未处理的雄性大鼠交配，并在整个孕期接受其食物配给量。尽管父本营养不足会降低雄性体重和成功交配率，但后代窝仔数、出生体重和21日龄时的体重并未显著改变。相比之下，母本营养不足与母体体重增加减少、后代出生体重降低以及断奶时体重降低有关。
