Bauer E P, von Segesser L K, Laske A, Turina M I
Klinik für Herzgefässchirurgie, Universitätsspital Zürich.
Helv Chir Acta. 1990 Oct;57(2):199-202.
Between 1979 and 1988 massive pulmonary embolism (PE) was treated surgically in 36 patients with extracorporeal circulation (ECC). Circulation was stable in 11 patients and unstable in 25; in this group 9 had previous resuscitation because of cardiac arrest. There were 7/36 early deaths (19%); 5 of those patients had to be resuscitated prior to surgery. Deaths were caused mainly by cerebral edema or hemorrhage. Significant complications occurred in 8 patients (28%). Diagnoses of PE was made clinically in most cases; confirmation by echocardiography was useful. Pulmonary angiography was made in patients with uncertain diagnosis and stable circulation. Operation is indicated in patients with unstable circulation and proved central PE; it is advisible in patients with embolism of the main pulmonary artery or its major branches. Hospital mortality is very high when the patient has to be resuscitated preoperatively; in this group surgery should be performed only in younger patients with a short period of resuscitation. Interruption of the inferior vena cava should be performed to prevent recurrent PE.
1979年至1988年间,36例大面积肺栓塞(PE)患者接受了体外循环(ECC)手术治疗。11例患者循环稳定,25例不稳定;该组中有9例曾因心脏骤停接受过复苏。有7/36例早期死亡(19%);其中5例患者在手术前必须进行复苏。死亡主要由脑水肿或出血引起。8例患者(28%)出现严重并发症。大多数病例通过临床诊断PE;超声心动图确诊很有用。对诊断不确定且循环稳定的患者进行了肺血管造影。对于循环不稳定且已证实为中心型PE的患者应进行手术;对于主肺动脉或其主要分支栓塞的患者建议进行手术。如果患者术前必须进行复苏,医院死亡率非常高;在这组患者中,仅应对复苏时间短的年轻患者进行手术。应进行下腔静脉阻断以预防复发性PE。