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[阿片类神经肽对大鼠感觉运动皮层细胞胆碱能和肾上腺素能反应性的影响]

[The effect of opioid neuropeptides on the cholino- and adrenoreactivity of the sensorimotor cortex cells in rats].

作者信息

Koshtoiants O Kh, Antipina M Iu, Kulikov M A

出版信息

Izv Akad Nauk SSSR Biol. 1990 Nov-Dec(6):889-94.

PMID:2074339
Abstract

The effect of two neuropeptides, dalargine and betaendorphine, on cholino- and adrenoreactivity of sensorimotor cortex cells has been studied in immobilized rats in acute experiments. Subcutaneous administration of the peptides led to redistribution of cells according to the type of their reaction and to changes in intensity of neuronal reactions to the applied neurotransmitters. The observed changes in chemoreactive properties of cortical neurons under the influence of the neuropeptides may play a certain part in the processes of learning and memory.

摘要

在急性实验中,对固定的大鼠研究了两种神经肽(达拉金和β - 内啡肽)对感觉运动皮层细胞胆碱能和肾上腺素能反应性的影响。皮下注射这些肽导致细胞根据其反应类型重新分布,并改变神经元对所施加神经递质反应的强度。在神经肽影响下观察到的皮层神经元化学活性特性的变化可能在学习和记忆过程中起一定作用。

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