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[大鼠皮层神经元对乙酰胆碱的反应性]

[Reactivity of the cortical neurons to acetylcholine in rats].

作者信息

Kotliar B I, Miasnikov A A, Medvedovskiĭ B V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Jan-Feb;36(1):156-62.

PMID:3705754
Abstract

Activity of 55 neurons of the sensorimotor cerebral cortex of rats was recorded at iontophoretic application of acetylcholine. 36% of neurons exhibited an excitatory reaction, 30%--inhibitory-excitatory, 18%--inhibitory-excitatory-inhibitory and 16%--excitatory-inhibitory reactions; the type of reaction, in contrast to its expressiveness, did not depend on the the type of reaction, in contrast to its expressiveness, did not depend on the strength of phoresis current. Duration of the excitatory components entering reactions of all neurons formed a continuous series of values in the range of 1.4 to 16 s and had 2 maxima--at the 4-th and 8-th seconds. It is suggested that duration of this component of reaction reflects important functional properties of the nerve cell.

摘要

在对大鼠感觉运动型大脑皮层的55个神经元进行离子电渗法施加乙酰胆碱时记录其活动。36%的神经元表现出兴奋性反应,30%为抑制性-兴奋性反应,18%为抑制性-兴奋性-抑制性反应,16%为兴奋性-抑制性反应;反应类型与其表现程度相反,不取决于电泳电流强度。所有神经元反应中兴奋性成分的持续时间在1.4至16秒范围内形成一个连续的值系列,并有两个最大值——在第4秒和第8秒。有人认为,这种反应成分的持续时间反映了神经细胞的重要功能特性。

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