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[沙眼衣原体相关扁桃体炎及罗他霉素抗菌治疗]

[Tonsillitis associated with Chlamydia trachomatis and antimicrobial therapy with rokitamycin].

作者信息

Ogawa H, Hashiguchi K, Kazuyama Y

机构信息

Division of Otorhinolayngology, Kitasato Institute Hospital.

出版信息

Kansenshogaku Zasshi. 1990 Dec;64(12):1535-41. doi: 10.11150/kansenshogakuzasshi1970.64.1535.

Abstract

Tonsillitis is the most common disease in the otorhinolaryngeal location. For most patients, tonsillitis is attributed to a group A streptococcal infection if the throat culture is positive for that organism or to a viral infection if the throat culture is negative. However, recent studies have shown that Chlamydia trachomatis can produce tonsillar infection. In this study, we evaluated the efficacy of Rokitamycin, a 16-membered ring macrolide antibiotic agent, in the treatment of tonsillitis associated with C. trachomatis. In 26 of 28 (92.9%) patients from whom C. trachomatis was isolated, the organism was eradicated by antimicrobial treatment with Rokitamycin of five days to three weeks' duration. In 25 of the 26 patients, they were totally free of tonsillar symptoms.

摘要

扁桃体炎是耳鼻咽喉部位最常见的疾病。对于大多数患者而言,如果咽喉培养物中该病原体呈阳性,扁桃体炎归因于A组链球菌感染;如果咽喉培养物呈阴性,则归因于病毒感染。然而,最近的研究表明沙眼衣原体可引发扁桃体感染。在本研究中,我们评估了16元环大环内酯类抗生素罗他霉素治疗沙眼衣原体相关性扁桃体炎的疗效。在分离出沙眼衣原体的28例患者中的26例(92.9%),通过使用为期5天至3周的罗他霉素抗菌治疗,该病原体被根除。在这26例患者中的25例,他们的扁桃体症状完全消失。

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