Soares I, Goldberg F, Massone E J, Soares I M
Department of Endodontics, Universidad de Santa Catarina, Florianopolis, Brazil.
J Endod. 1990 Apr;16(4):166-9. doi: 10.1016/S0099-2399(06)81964-3.
One-hundred twenty root canals of dog teeth were cleaned, shaped, and obturated with gutta-percha and sealers using a lateral condensation technique. The sealers used were Sealapex, CRCS, and zinc oxide-eugenol. The animals were killed after 30 or 180 days and the specimens were examined histologically. Sealapex and CRCS caused a periapical tissue response similar to that found with the zinc oxide-eugenol. An ingrowth of connective tissue infiltrated with chronic inflammatory cells was noticed in cases where the filling material reached the apical stops. Regardless of sealer used, deposition of new hard tissue along the apical root canal walls was observed, which caused the partial closure of the apical opening. In the Sealapex and CRCS groups, sealer particles were found at a considerable distance from the apices. All overfilled specimens caused chronic inflammatory reactions in the periapical tissues.
使用侧向加压技术，对120颗犬齿根管进行清理、塑形，并用牙胶尖和封闭剂进行充填。所用封闭剂为Sealapex、CRCS和氧化锌丁香酚。30天或180天后处死动物，对标本进行组织学检查。Sealapex和CRCS引起的根尖周组织反应与氧化锌丁香酚相似。当充填材料到达根尖止点时，可见结缔组织向内生长并浸润慢性炎症细胞。无论使用何种封闭剂，均观察到沿根尖根管壁有新的硬组织沉积，导致根尖孔部分封闭。在Sealapex和CRCS组中，在距根尖相当远的距离处发现了封闭剂颗粒。所有超充标本均在根尖周组织中引起慢性炎症反应。
