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[辐射化学防护剂的研究。第三十篇。蛇床子的辐射防护物质]

[Studies on chemical protectors against radiation. XXX. Radioprotective substances of cnidii rhizoma].

作者信息

Ohta S, Sakurai N, Sato Y, Inoue T, Shinoda M

机构信息

Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan.

出版信息

Yakugaku Zasshi. 1990 Oct;110(10):746-54. doi: 10.1248/yakushi1947.110.10_746.

Abstract

Radiation protective effects of the methanol extract and its fractions of Cnidii Rhizoma on lethality and skin injury induced by X-irradiation were studied. As a result of these studies, it was observed that significant protective effects exist in both ether and water soluble portions prepared from the above methanol extract, and two of the active principles in the ether and water soluble ones were identified as ferulic acid and adenosine, respectively.

摘要

研究了蛇床子甲醇提取物及其各馏分对X射线照射所致致死率和皮肤损伤的辐射防护作用。通过这些研究发现,上述甲醇提取物制备的乙醚可溶部分和水溶部分均存在显著的防护作用,且已分别鉴定出乙醚可溶部分和水溶部分中的两种活性成分是阿魏酸和腺苷。

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