Yamahara J, Kitani T, Kobayashi H, Kawahara Y
Kyoto Pharmaceutical University, Japan.
Yakugaku Zasshi. 1990 Dec;110(12):932-5. doi: 10.1248/yakushi1947.110.12_932.
During screening for the development of drugs from natural products, methanolic extract of tuber of Stachys sieboldii MIQ. (Labiatae) significantly inhibited the lethal induced by KCN in mice. The methanolic extract was fractionated by column chromatography to identify the active constituents. Acteoside and stachysoside C, phenylethanoid glycoside, have a significant effect on the KCN-induced anoxia model.
在从天然产物中开发药物的筛选过程中，水苏（唇形科）块茎的甲醇提取物显著抑制了氰化钾对小鼠的致死作用。通过柱色谱法对甲醇提取物进行分离，以鉴定其活性成分。毛蕊花糖苷和水苏糖苷C（苯乙醇苷）对氰化钾诱导的缺氧模型有显著影响。
