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[分化型甲状腺癌]

[Differentiated thyroid cancer].

作者信息

Chifan M, Strat V, Tîrcoveanu E, Niculescu D, Bordea M, Georgescu S, Zbranca E, Dobrescu G, Florea N, Baran T

机构信息

Clinica I-a chirurgie, Institutul de Medicină şi Farmacie Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1990 Jan-Mar;94(1):109-12.

PMID:2075308
Abstract

In the interval 1979-1988, out of 1070 operated goiters 77 malignant thyroid tumors were recorded, 60 of them being differentiated: papillary--32 (53.4%), vesicular--12 (20%), mixed forms--16 (26.7%). The differentiated thyroid carcinomas had peculiar clinical biological and prognostic features and were framed: stage I--60%, stage II--23.4% and state III-IV--16.6%. Only 15 cases presented lymph node metastases. In 16 cases the thyroid tumor was associated with another thyropathy: Hashimoto's thyroiditis--5 cases, Basedow's disease--1 case. The surgical intervention was performed in two times: first total lobectomy or total lobo-isthmectomy [correction of lobioistectomy] with contralateral subtotal exeresis, then total thyroidectomy. It is insisted upon a careful surveillance of postoperative evolution (clinical, biological, scintigraphy) in order to detect the recurrence and apply a proper treatment.

摘要

在1979年至1988年期间,1070例接受手术的甲状腺肿中,记录到77例甲状腺恶性肿瘤,其中60例为分化型:乳头状癌32例(53.4%),滤泡状癌12例(20%),混合型16例(26.7%)。分化型甲状腺癌具有独特的临床生物学和预后特征,分期情况如下:I期占60%,II期占23.4%,III - IV期占16.6%。仅有15例出现淋巴结转移。16例甲状腺肿瘤合并有其他甲状腺疾病:桥本甲状腺炎5例,突眼性甲状腺肿1例。手术分两步进行:首先行全叶切除术或全叶 - 峡部切除术[纠正为叶 - 峡部切除术]及对侧次全切除术,然后行全甲状腺切除术。强调要对术后病情演变(临床、生物学、闪烁扫描)进行仔细监测,以便发现复发并采取适当治疗措施。

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1
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Rev Med Chir Soc Med Nat Iasi. 1990 Jan-Mar;94(1):109-12.
2
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[Prospective therapy study in differentiated thyroid carcinoma].[分化型甲状腺癌的前瞻性治疗研究]
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Management of papillary microcarcinoma of the thyroid.甲状腺微小乳头状癌的管理
S D Med. 2006 Oct;59(10):425-7.
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[Small thyroid carcinomas: biological characteristics, diagnosis and therapy].[微小甲状腺癌:生物学特性、诊断与治疗]
Schweiz Med Wochenschr. 1999 May 8;129(18):681-90.
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[Thyroid carcinoma. Criteria for the selection of surgical treatment].[甲状腺癌。手术治疗的选择标准]
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10
[Significance of lymph node metastases of differentiated thyroid gland carcinomas and C-cell carcinomas for prognosis--a meta-analysis].[分化型甲状腺癌和C细胞癌淋巴结转移对预后的意义——一项荟萃分析]
Zentralbl Chir. 1997;122(4):259-65.