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[120例男性系统性红斑狼疮患者的生存分析]

[An analysis of the survival of 120 male patients with systemic lupus erythematosus].

作者信息

Folomeev M Iu, Alekberova Z S

出版信息

Revmatologiia (Mosk). 1990 Oct-Dec(4):17-9.

PMID:2075348
Abstract

The aim of the study was to evaluate survival rates and causes of death of a large group of male patients with systemic lupus erythematosus (SLE). The group consisted of 120 patients with evident SLE that were observed at the Institute of Reanimatology from 1976 to 1989; the mean age was 31.3 years; the mean age for the disease onset was 29.6 years; the mean follow-up duration was 9.1 years. The survival pattern was obtained with the method of the life table analysis. Maximum lethality was observed during the first years of the disease: in 1-4 years 11 patients died, in 5-6 years--6 patients, and in 8-12 years--7 patients; 27 patients died during the follow-up period, 17--died of lupus nephritis, 4--of neurological involvement, one patient--of heart insufficiency, one--of lung tuberculosis, one--of ischemic heart disease, one--of amyloidosis, one--of sepsis and one patient died of chronic lung insufficiency.

摘要

该研究的目的是评估一大群男性系统性红斑狼疮(SLE)患者的生存率和死亡原因。该组由120例确诊为SLE的患者组成,于1976年至1989年在复苏医学研究所进行观察;平均年龄为31.3岁;疾病发病的平均年龄为29.6岁;平均随访时间为9.1年。采用生命表分析法得出生存模式。在疾病的最初几年观察到最高死亡率:1至4年有11例患者死亡,5至6年有6例,8至12年有7例;随访期间有27例患者死亡,17例死于狼疮性肾炎,4例死于神经受累,1例死于心力衰竭,1例死于肺结核,1例死于缺血性心脏病,1例死于淀粉样变性,1例死于败血症,1例死于慢性肺功能不全。

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