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[关于猫的中枢视觉通路的电诱发反应(EER)分析(1)。猫EER的波形]

[Analysis of electrically evoked response (EER) in relation to the central visual pathway of the cat (1). Wave shape of the cat EER].

作者信息

Fukatsu Y, Miyake Y, Sugita S, Saito A, Watanabe S

机构信息

Eye Clinic, Toyota Memorial Hospital.

出版信息

Nippon Ganka Gakkai Zasshi. 1990 Nov;94(11):993-1000.

PMID:2075876
Abstract

To analyze the Electrically evoked response (EER) in relation to the central visual pathway, the authors studied the properties of wave patterns and peak latencies of EER in 35 anesthetized adult cats. The cat EER showed two early positive waves on outward current (cornea cathode) stimulus and three or four early positive waves on inward current (cornea anode) stimulus. These waves were recorded within 50 ms after stimulus onset, and were the most consistent components in cat EER. The stimulus threshold for EER showed a less individual variation than amplitude. The difference of stimulus threshold between outward and inward current stimulus was also essentially negligible. The stimulus threshold was higher in early components than in late components. The peak latency of EER became shorter and the amplitude became higher, as the stimulus intensity was increased. However, this tendency was reversed and some wavelets started to appear when the stimulus was extremely strong. The recording using short stimulus duration and bipolar electrodes enabled us to reduce the electrical artifact of EER. These results obtained from cats were compared with those of humans and rabbits.

摘要

为了分析与中枢视觉通路相关的电诱发反应(EER),作者研究了35只麻醉成年猫的EER波形特征和峰值潜伏期。猫的EER在向外电流(角膜阴极)刺激时显示出两个早期正向波,在向内电流(角膜阳极)刺激时显示出三个或四个早期正向波。这些波在刺激开始后50毫秒内记录到,是猫EER中最稳定的成分。EER的刺激阈值个体差异比幅度小。向外和向内电流刺激的刺激阈值差异也基本可以忽略不计。早期成分的刺激阈值高于晚期成分。随着刺激强度增加,EER的峰值潜伏期变短,幅度变大。然而,当刺激极强时,这种趋势会逆转,一些小波开始出现。使用短刺激持续时间和双极电极进行记录使我们能够减少EER的电伪迹。将从猫身上获得的这些结果与人类和兔子的结果进行了比较。

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