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[血液吸附对腹腔器官破坏性疾病中自由基氧化活性的影响]

[The effect of hemosorption on the activity of free radical oxidation in destructive diseases of the abdominal cavity organs].

作者信息

Koniukhova S G, Dubikaĭtis A Iu, Strashnov V I, Belotserkovskiĭ M V

出版信息

Anesteziol Reanimatol. 1990 Nov-Dec(6):48-52.

PMID:2075933
Abstract

Depletion of antioxidant system which accompanies excessive formation of oxygen radicals and increased activity of lipid peroxidation in destructive diseases of the abdominal organs leads to the generalization of the pathological process and severe endogenous intoxication. Hemosorption as part of intensive therapy in patients with peritonitis ensures a decrease in endotoxemia degree due to elimination of toxic LPO metabolites from the blood flow and stabilizes in the post-hemosorption period the activity of free radical reactions due to an increase in antioxidant activity.

摘要

腹部器官破坏性疾病中,抗氧化系统耗竭伴随着氧自由基过度生成和脂质过氧化活性增加,导致病理过程泛化和严重的内源性中毒。血液吸附作为腹膜炎患者强化治疗的一部分,由于从血流中清除了有毒的脂质过氧化代谢产物,可确保内毒素血症程度降低,并在血液吸附后阶段通过增加抗氧化活性稳定自由基反应的活性。

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1
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Anesteziol Reanimatol. 1990 Nov-Dec(6):48-52.
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