Browning J W, Mein G A, Barton M, Nicholls T J, Brightling P
Victorian Mastitis Research Group, Department of Agriculture and Rural Affairs, Bairnsdale, Victoria.
Aust Vet J. 1990 Dec;67(12):440-2. doi: 10.1111/j.1751-0813.1990.tb03055.x.
Four strategies for selecting cows for intramammary therapy with benzathine cloxacillin at drying off were compared in 12 Victorian dairy herds. The bacteriological status of all quarters of all (1044) cows was determined just before drying off, within 2 d of calving, and again 3 to 5 months after calving. All cases of clinical mastitis (from calving to mid-lactation) were recorded. Cows not infected at drying off were allocated randomly to 2 subgroups of approximately 350 cows each: not infected, not treated (NI-NT), or not infected, all quarters treated (NI-AT). New infection rates in the dry period (3.8% for NI-NT vs 2.1% for NI-AT) and in early lactation (4.1% for NI-NT vs 3.9% for NI-AT) were low and these differences were not significant. Incidence of clinical mastitis in early lactation was almost 50% higher for the treated group of uninfected cows compared with the untreated group (0.05 less than p less than 0.1). Cows infected in one or more quarters at drying off were split randomly into 2 subgroups of approximately 170 cows each: infected, all quarters treated (I-AT), or infected quarters treated only (I-QT). The new infection rate during the dry period was nearly 4 times higher for I-QT (15.3%) due to significantly more new infections by Staphylococcus aureus and Streptococcus uberis.(ABSTRACT TRUNCATED AT 250 WORDS)
在12个维多利亚州奶牛场中，比较了干奶期选用苄星氯唑西林进行乳房内治疗的奶牛的四种策略。在干奶前、产犊后2天内以及产犊后3至5个月时，确定了所有（1044头）奶牛所有乳腺的细菌学状况。记录了所有临床乳腺炎病例（从产犊到泌乳中期）。干奶时未感染的奶牛被随机分配到两个亚组，每组约350头奶牛：未感染，未治疗（NI-NT），或未感染，所有乳腺治疗（NI-AT）。干奶期（NI-NT为3.8%，NI-AT为2.1%）和泌乳早期（NI-NT为4.1%，NI-AT为3.9%）的新感染率较低，且这些差异不显著。与未治疗组相比，未感染奶牛的治疗组在泌乳早期临床乳腺炎的发病率高出近50%（0.05＜p＜0.1）。干奶时一个或多个乳腺感染的奶牛被随机分为两个亚组，每组约170头奶牛：感染，所有乳腺治疗（I-AT），或仅感染的乳腺治疗（I-QT）。由于金黄色葡萄球菌和乳房链球菌引起的新感染显著增多，I-QT在干奶期的新感染率几乎高出4倍（15.3%）。（摘要截短于250字）
