de la Fuente M, Martin M I, Ortega E
Department of Animal Biology II (Animal Physiology), Faculty of Biological Science, Complutense University, Badajoz, Spain.
Comp Immunol Microbiol Infect Dis. 1990;13(4):189-98. doi: 10.1016/0147-9571(90)90087-a.
The effect of acute physical exercise (swimming until exhaustion) on the phagocytic function of peritoneal macrophages from old adult BALB/c mice (55 +/- 5 weeks old) was studied. Adherence capacity of macrophages to substrate, spontaneous mobility and chemotaxis as well as digestion capacity measured by nitroblue tetrazolium (NBT) reduction in presence of ingested material (latex beads) were not modified with exercise. Adherence to nylon fiber, opsonization and ingestion of Candida albicans (either spontaneous or in presence of serum), ingestion of latex particles as well as nitroblue tetrazolium (NBT) reduction in absence of ingested material (oxidative metabolism measure) were increased in respect to controls with statistically significant differences (P less than 0.001) in peritoneal macrophages after the exercise.
研究了急性体育锻炼（游泳至力竭）对老年成年BALB/c小鼠（55±5周龄）腹腔巨噬细胞吞噬功能的影响。巨噬细胞对底物的黏附能力、自发运动性和趋化性，以及在摄入物质（乳胶珠）存在下通过硝基蓝四氮唑（NBT）还原测定的消化能力，均未因运动而改变。与对照组相比，运动后腹腔巨噬细胞对尼龙纤维的黏附、调理作用以及白色念珠菌的吞噬（自发或在血清存在下）、乳胶颗粒的吞噬以及在无摄入物质情况下的硝基蓝四氮唑（NBT）还原（氧化代谢测定）均增加，且具有统计学显著差异（P<0.001）。
