[Effect of human semen and vaginal bacteria culture fluid on induction of cervical cancer in mice].

The effect of human semen and culture fluid of bacteria (SB) isolated from the cervix of carcinoma patients on the induction of cervical carcinoma by 20-methylcholanthrene (MCA) in mice was studied. It was found that cervical carcinoma could be induced by SB with an induction rate of 12%. That by MCA alone was 11.8% whereas the SB positive for inducing EB virus EA in Raji cells used in combination with MCA gave an induction rate of 54.2%. The experimental results indicated that SB was both carcinogenic and tumor promoting. The possible mechanism of action of SB is discussed.