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[严重机械性创伤后早期氧平衡状态在休克肺综合征发病机制中的重要性]

[The importance of the state of the oxygen balance in the early period following severe mechanical trauma in the pathogenesis of the shock lung syndrome].

作者信息

Vasilenko N I, Edeleva N V

出版信息

Anesteziol Reanimatol. 1990 Jul-Aug(4):50-3.

PMID:2077970
Abstract

To elucidate the role of oxygen balance disturbances in the pathogenesis of shock lung syndrome (SLS) central hemodynamic parameters, arterial and mixed venous blood content, O2 transport (TO2) and consumption (VO2), TO2 reserve have been studied in 95 patients after trauma. Two groups of patients have been identified: group I--control (n = 48); and group II--patients with SLS (n = 47). Significant differences in central hemodynamics and oxygen balance between the groups before the manifestation of SLS symptoms were lower values of the cardiac output, TO2, VO2 and TO2 reserve in patients of group II. If, on the first day after trauma, there was hyperdynamic type of circulation and 40-50% increased (as compared to the physiological norm) VO2 in combination with sufficient TO2 reserve (about 100 ml/(min.m2) the likelihood of SLS onset was considerably reduced.

摘要

为阐明氧平衡紊乱在休克肺综合征(SLS)发病机制中的作用,对95例创伤后患者的中心血流动力学参数、动脉血和混合静脉血含氧量、氧运输(TO2)和消耗(VO2)、TO2储备进行了研究。确定了两组患者:第一组——对照组(n = 48);第二组——SLS患者(n = 47)。在SLS症状出现之前,两组之间中心血流动力学和氧平衡的显著差异在于,第二组患者的心输出量、TO2、VO2和TO2储备值较低。如果在创伤后的第一天出现高动力型循环,且VO2比生理正常值增加40 - 50%,同时伴有足够的TO2储备(约100 ml/(min·m2)),则SLS发病的可能性会大大降低。

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