Zolotokrylina E S, Vasilenko N I, Morozov N V
Anesteziol Reanimatol. 1989 May-Jun(3):19-22.
116 patients with massive blood loss and trauma have been studied in intensive care units. It has been established that the main reason for the onset of hypoxemia in "shock lung" is disturbed gas exchange in the lungs due to an expanded physiological dead space (VD/VT) and blood shunting in the lungs (QS/QT). Intravascular blood coagulation is one of the main reasons for the development and maintenance of systemic hypoperfusion in the lung tissue. Progressive increase in venous admixture during inhalation of 100% oxygen over a five-day treatment period is due to an increased number of still blood-supplied but already unventilated affected alveoli.
116例大出血和创伤患者在重症监护病房接受了研究。已经确定，“休克肺”中低氧血症发生的主要原因是生理性死腔扩大（VD/VT）和肺内血液分流（QS/QT）导致肺内气体交换紊乱。血管内凝血是肺组织中全身低灌注发生和维持的主要原因之一。在为期五天的治疗期间，吸入100%氧气时静脉混合血逐渐增加是由于仍有血液供应但已无通气的受累肺泡数量增加所致。
