Rusko J, Bolton T B, Aaronson P, Bauer V
Institute of Experimental Pharmacology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Eur J Pharmacol. 1990 Aug 10;184(2-3):325-8. doi: 10.1016/0014-2999(90)90626-h.
Spontaneous transient and evoked outward currents were studied using the whole cell patch-clamp technique with freshly dispersed smooth muscle cells isolated from rabbit and guinea pig taenia caeci. Phenylephrine induced a low amplitude sustained outward current in both tissues. Simultaneously, the frequency and amplitude of spontaneous transient outward currents were increased. However, there were differences between the effects of phenylephrine on the evoked outward currents recorded from smooth muscle cells of rabbit (reduction) and guinea pig (enhancement) taenia caeci.
使用全细胞膜片钳技术，对从兔和豚鼠盲肠带分离出的新鲜分散的平滑肌细胞进行自发性瞬态电流和诱发外向电流的研究。去氧肾上腺素在两种组织中均诱导出低幅度的持续性外向电流。同时，自发性瞬态外向电流的频率和幅度增加。然而，去氧肾上腺素对兔（降低）和豚鼠（增强）盲肠带平滑肌细胞记录的诱发外向电流的影响存在差异。
