Pisani M, Ruocco V, Sacerdoti G
Clinica Dermosifilopatica, I Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II.
G Ital Dermatol Venereol. 1990 Sep;125(9):409-12.
Idiopathic hypereosinophilic syndrome (IHS) is reported in a 59-year-old farmer. Skin manifestations were represented by pruritic erythemato-squamous and papulonodular lesions, the heart was affected by endomyocardic fibrosis, and periodic intestinal colics denoted a possible gut involvement. A mild and transient beneficial effect was achieved by treatment with antihistamines, sodium-chromoglycate, steroids. Recent studies indicate that IHS hypereosinophilia is caused by interleukins 3 and 5, cytokines able to activate circulating eosinophils and to enhance the survival of these cells.
