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[Therapy of pediatric infections with cefixime].

作者信息

Helwig H

机构信息

Fachabteilung für Kinderheilkunde und Jugendmedizin des St.-Josefs-Krankenhauses, Freiburg, Germany.

出版信息

Infection. 1990;18 Suppl 3:S147-9. doi: 10.1007/BF01644635.

DOI:10.1007/BF01644635
PMID:2079376
Abstract

In a pilot study with a limited number of patients the efficacy and tolerance of cefixime, a new oral cephalosporin antibiotic, were investigated in 15 children with the clinical diagnosis of bacterial respiratory tract infection, otitis media or urinary tract infection. The dosage was 2 x 4 mg/kg body weight daily for a period of seven to 11 days. Clinical efficacy was good in 13 cases, and subjective tolerance was good in all cases. The results support the assumption that cefixime is suited for the treatment of children with bacterial infections of the airways and urinary tract with sensitive pathogens.

摘要

相似文献

1
[Therapy of pediatric infections with cefixime].
Infection. 1990;18 Suppl 3:S147-9. doi: 10.1007/BF01644635.
2
Cefixime in the treatment of respiratory and urinary tract infections.头孢克肟治疗呼吸道和泌尿系统感染。
Chemotherapy. 1998 Sep;44 Suppl 1:31-4. doi: 10.1159/000048462.
3
[Clinical studies on cefixime in pediatrics].
Jpn J Antibiot. 1986 Apr;39(4):1149-56.
4
[Clinical experience with cefixime in the pediatric infections].[头孢克肟在儿科感染中的临床经验]
Jpn J Antibiot. 1986 Apr;39(4):1128-37.
5
[Clinical studies on cefixime in pediatrics].头孢克肟在儿科的临床研究
Jpn J Antibiot. 1989 Dec;42(12):2527-39.
6
[Fundamental and clinical studies of cefixime in children].儿童头孢克肟的基础与临床研究
Jpn J Antibiot. 1986 Apr;39(4):1202-13.
7
[Effectiveness and tolerance of cefixime in bacterial infections in the ENT area].
Infection. 1990;18 Suppl 3:S122-4. doi: 10.1007/BF01644629.
8
[Clinical experience with cefixime in the pediatric field].[头孢克肟在儿科领域的临床经验]
Jpn J Antibiot. 1986 Apr;39(4):1138-48.
9
[Clinical evaluation of cefixime in children].[头孢克肟在儿童中的临床评估]
Jpn J Antibiot. 1986 Apr;39(4):1007-19.
10
[Clinical efficacy of cefixime (results of multicenter trials)].
Antibiot Khimioter. 1993 Jun;38(6):45-50.

本文引用的文献

1
Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children.头孢克肟与头孢克洛治疗婴幼儿急性中耳炎的对比研究
Pediatr Infect Dis J. 1987 Oct;6(10):992-6. doi: 10.1097/00006454-198710000-00041.
2
Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media.
Pediatr Infect Dis J. 1987 Oct;6(10):989-91. doi: 10.1097/00006454-198710000-00040.
3
Pharmacokinetic profile of cefixime in man.头孢克肟在人体内的药代动力学特征。
Pediatr Infect Dis J. 1987 Oct;6(10):963-70. doi: 10.1097/00006454-198710000-00035.
4
In vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime.新型广谱、β-内酰胺酶稳定口服头孢菌素——头孢克肟的体外活性
Pediatr Infect Dis J. 1987 Oct;6(10):958-62. doi: 10.1097/00006454-198710000-00034.
5
Cefixime: spectrum of antibacterial activity against 16,016 clinical isolates.头孢克肟:对16016株临床分离菌的抗菌活性谱
Pediatr Infect Dis J. 1987 Oct;6(10):954-7.
6
Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion.头孢克肟与阿莫西林治疗急性分泌性中耳炎的随机、开放标签、多中心试验
Pediatr Infect Dis J. 1987 Oct;6(10):997-1001. doi: 10.1097/00006454-198710000-00042.
7
Safety profile of cefixime.
Pediatr Infect Dis J. 1987 Oct;6(10):976-80. doi: 10.1097/00006454-198710000-00037.
8
Noncomparative, open label, multicenter trial of cefixime for treatment of bacterial pharyngitis, cystitis and pneumonia in pediatric patients.头孢克肟治疗小儿细菌性咽炎、膀胱炎和肺炎的非对照、开放标签、多中心试验。
Pediatr Infect Dis J. 1987 Oct;6(10):1002-6. doi: 10.1097/00006454-198710000-00043.