Kader K L, Hubbard S, Carroll B A
Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Invest Radiol. 1990 Oct;25(10):1091-4. doi: 10.1097/00004424-199010000-00004.
A study measuring in vivo three quantitative parameters of human liver was performed to assess the feasibility of measuring these parameters using standard ultrasound equipment and technique and to evaluate their potential for diagnosing diffuse liver disease. The parameters measured were: (1) d-bar, the average scatter spacing between semiperiodic scatterer; (2) r, a measure of the relative scattering strength; and (3) sigma, a measure of the variability in the relative scattering strength. Using linear discriminant and multivariate analysis, the above parameters are able to significantly separate normal livers from those with cirrhosis. This technique shows promise in the clinical identification of diffuse liver disease.
进行了一项测量人体肝脏体内三个定量参数的研究，以评估使用标准超声设备和技术测量这些参数的可行性，并评估它们在诊断弥漫性肝病方面的潜力。所测量的参数为：（1）d-bar，半周期散射体之间的平均散射间距；（2）r，相对散射强度的度量；（3）sigma，相对散射强度变异性的度量。使用线性判别分析和多变量分析，上述参数能够显著区分正常肝脏和肝硬化肝脏。这项技术在弥漫性肝病的临床识别中显示出前景。
