Mercuri O, De Tomas M E
Lipids. 1978 Apr;13(4):289-90. doi: 10.1007/BF02533672.
The activity of delta9 desaturase was determined in the microsomal fraction of normal mouse liver and hepatoma SS1K in the presence of the 105,000 x g supernatant. Neither hepatic nor hepatoma soluble fractions were able to modify the low desaturating capacity. Two enzymes from the microsomal electron transport chain associated with delta9 desaturase, namely NADH-cytochrom b5 reductase and NADH-cytochrom C reductase were also measured. The results indicate that the low delta9 desaturase activity in hepatoma SS1K could be related to the reduced amount of desaturase.
在105,000×g上清液存在的情况下，测定了正常小鼠肝脏微粒体部分和肝癌SS1K中δ9去饱和酶的活性。肝脏和肝癌的可溶性部分均无法改变低去饱和能力。还测定了微粒体电子传递链中与δ9去饱和酶相关的两种酶，即NADH-细胞色素b5还原酶和NADH-细胞色素C还原酶。结果表明，肝癌SS1K中δ9去饱和酶活性低可能与去饱和酶数量减少有关。
