Division of Neurosurgery, Dalhousie University, Halifax, Nova Scotia, Canada.
J Neurotrauma. 2011 Aug;28(8):1509-14. doi: 10.1089/neu.2009.1155-A. Epub 2010 Aug 26.
A systematic review of the literature was performed to address pertinent clinical questions regarding deep vein thrombosis (DVT) prophylaxis in the setting of acute spinal cord injury (SCI). Deep vein thromboses are a common occurrence following SCI. Administration of low-molecular-weight heparin (LMWH) within 72 h of injury is recommended to minimize the occurrence of DVT. Furthermore, when surgical intervention is required, LMWH should be held the morning of surgery, and resumed within 24 h post-operatively.
系统回顾了文献,以解决有关急性脊髓损伤(SCI)背景下深静脉血栓形成(DVT)预防的相关临床问题。SCI 后深静脉血栓形成很常见。建议在损伤后 72 小时内给予低分子量肝素(LMWH)以最大程度地减少 DVT 的发生。此外,当需要手术干预时,应在手术当天早晨停止使用 LMWH,并在术后 24 小时内恢复使用。