Department of Surgery, Asahikawa Medical University, Asahikawa Hokkaido 078-8510, Japan.
World J Surg Oncol. 2010 Aug 26;8:74. doi: 10.1186/1477-7819-8-74.
Adenoid cystic carcinoma of the peripheral lung is a rare entity. We recently encountered a patient with adenoid cystic carcinoma. A 75-year-old woman showed a nodular lesion with 10 mm in diameter in the right upper lung field on chest radiography. The diagnosis was unclear, but lung cancer could not be ruled out. Thoracoscopic biopsy was performed, and intraoperative pathological diagnosis revealed the carcinoma of the lung. We enforced upper lobectomy and mediastinal lymph node dissection to the patient. Histopathological examination revealed adenoid cystic carcinoma with a characteristic cribriform structure. Immunohistochemical examination revealed that the tumor cells were positive for thyroid transcription factor 1 (TTF-1), this tumor was diagnosed primary ACC of the lung.
肺外周部腺样囊性癌是一种罕见的实体瘤。我们最近遇到了一位患有腺样囊性癌的患者。一位 75 岁女性在胸部 X 线摄影中显示右肺上野有一个直径为 10 毫米的结节状病变。诊断不明确,但不能排除肺癌。对患者进行了胸腔镜活检,术中病理诊断为肺癌。我们对患者实施了肺上叶切除术和纵隔淋巴结清扫术。组织病理学检查显示具有特征性筛状结构的腺样囊性癌。免疫组织化学检查显示肿瘤细胞甲状腺转录因子 1(TTF-1)阳性,该肿瘤被诊断为原发性肺腺样囊性癌。