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肺腺样囊性癌甲状腺转移:一例报告及文献复习

Thyroid metastasis from adenoid cystic carcinoma of the lung: a case report and literature review.

作者信息

Montecamozzo Giulio, Cammarata Francesco, Pennacchi Luca, Yakushkina Al'ona, Carsana Luca, Zerbi Pietro, Danelli Piergiorgio

机构信息

Department of General Surgery, Luigi Sacco University Hospital, 20157 Milan, Italy.

Department of General Surgery, Ospedale di Saronno, 21047 Saronno VA, Italy.

出版信息

J Surg Case Rep. 2021 May 20;2021(5):rjab178. doi: 10.1093/jscr/rjab178. eCollection 2021 May.

Abstract

Both adenoid cystic carcinoma (ACC) and thyroid metastasis are quite peculiar clinical presentations. ACC is a malignant salivary gland-type tumour mostly found in the head and neck district, but that can arise from different organs. Due to its rarity, it can pose problems in the diagnostic and therapeutic management. A 72-year-old woman presented for a persistent non-productive cough. A computed tomography showed a lung mass. She underwent lung surgery, and the lesion was an ACC primitive of the lung. She developed hoarseness and ultrasound and cytology confirmed metastatic involvement of left thyroid lobe from ACC. A total thyroidectomy was performed, followed by radiotherapy. The present case highlights the need to be aware of possible metastatic thyroid localization of ACC originating in lower airways. This is a very rare event, and clinical and cytological findings must be carefully examined. It represents an opportunity to consider the current knowledge about ACC metastasis to thyroid.

摘要

腺样囊性癌(ACC)和甲状腺转移瘤都是颇为特殊的临床表现。ACC是一种恶性唾液腺型肿瘤,大多见于头颈部区域,但也可能起源于不同器官。因其罕见,在诊断和治疗管理方面可能会出现问题。一名72岁女性因持续性干咳前来就诊。计算机断层扫描显示肺部有一肿块。她接受了肺部手术,病变为原发性肺ACC。她出现了声音嘶哑,超声和细胞学检查证实左甲状腺叶有ACC转移。遂进行了全甲状腺切除术,随后进行放疗。本病例强调了需要意识到起源于下呼吸道的ACC可能转移至甲状腺。这是一种非常罕见的情况,必须仔细检查临床和细胞学检查结果。它为思考目前关于ACC转移至甲状腺的知识提供了一个契机。

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