Imoto S, Ito M, Nakagawa T
Department of Internal Medicine, Hyogo Medical Center For Adults.
Rinsho Ketsueki. 1990 Dec;31(12):1945-9.
A 20-year-old man was admitted because of general fatigue. Peripheral blood examination revealed pancytopenia (WBC 1,700/microliters, RBC 210 x 10(4)/microliters, Plt 3.2 x 10(4)/microliters) with remarkable erythroblastosis. Bone marrow examination revealed erythroid hyperplasia and an increase of abnormal myeloblasts with Auer bodies (37% of non erythroid cells). A diagnosis of erythroleukemia (AML M6) was made. He received two courses of combination chemotherapy (BHAC-DMP and VAMA (VP-16, Ara-C, 6-MP, and doxorubicin (ADR)) but complete remission (CR) could not be achieved. Consequently, he was treated with LDAC. After two courses of LDAC. CR was obtained. Subsequently, he received two courses of HDAC as consolidation, and therapy has been off thereafter. He remains in CR state for more than 12 months.
一名20岁男性因全身乏力入院。外周血检查显示全血细胞减少（白细胞1700/微升，红细胞210×10⁴/微升，血小板3.2×10⁴/微升），伴有明显的幼红细胞增多。骨髓检查显示红系增生，出现异常原粒细胞并伴有奥氏小体增多（占非红系细胞的37%）。诊断为红白血病（AML M6）。他接受了两个疗程的联合化疗（BHAC - DMP和VAMA（依托泊苷、阿糖胞苷、6 - 巯基嘌呤和阿霉素（ADR）），但未达到完全缓解（CR）。因此，他接受了低剂量阿糖胞苷（LDAC）治疗。经过两个疗程的LDAC治疗后，获得了CR。随后，他接受了两个疗程的大剂量阿糖胞苷（HDAC）作为巩固治疗，此后停止治疗。他处于CR状态已超过12个月。
