Razzakov S M, Krakovskiĭ M E, Ashirmetov A Kh
Khirurgiia (Mosk). 1990 Dec(12):11-5.
The authors studied the unspecific resistance of the organism according to the ratio of the formed elements of the blood, the detoxification function of the liver by the antipyrine test and evaluation of the acetylation capacity, as well as the leukocyte intoxication index in 42 patients with various types of acute ileus (obstructive, strangulation, dynamic). Ileus was found to reduce the unspecific resistance and the acetylation capacity of the patient's organism with the increased leukocyte intoxication index. In patients with obstructive ileus the antipyrine half-life was increased and was not normalized during treatment. The postoperative period in patients with a marked diminution of unspecific resistance and acetylation capacity of the organism with an increase in the leukocyte intoxication index and antipyrine half-life was characterized by an unfavourable course and the development of various purulent complications.
作者根据血液有形成分的比例、通过安替比林试验评估肝脏的解毒功能及乙酰化能力,以及对42例不同类型急性肠梗阻(梗阻性、绞窄性、动力性)患者的白细胞中毒指数,研究了机体的非特异性抵抗力。结果发现,肠梗阻会降低患者机体的非特异性抵抗力和乙酰化能力,同时白细胞中毒指数升高。在梗阻性肠梗阻患者中,安替比林半衰期延长,且在治疗期间未恢复正常。机体非特异性抵抗力和乙酰化能力显著降低、白细胞中毒指数和安替比林半衰期升高的患者,术后病程不利,会出现各种化脓性并发症。