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[测定手术患者红细胞内钾水平的临床价值]

[Clinical value of determining potassium level in erythrocytes of operated-on patients].

作者信息

Popovich M, Dugalich D, Krivokapich Z

出版信息

Khirurgiia (Mosk). 1990 Dec(12):75-7.

PMID:2079824
Abstract

Since potassium ions are very important in surgical pathology and the course of the postoperative period, the authors determined erythrocyte potassium in 211 patients (37 in the control group and in 174 in the pathological group). The statistically evaluated results were compared for both groups and the correlations of serum and red cell potassium with the acid-base status were studied. The authors used a Marongiu's modified method of potassium determination in a erythrocyte hemolysate with a flame photometer. The mean values for both the control and pathological groups were 84.61 (SD 5.24) and 85.98 (SD 9.10), respectively. The correlation of serum and erythrocyte potassium is subject to many influences and occurs only in the limited pH and HCO3 intervals (pH 7.4 +/- 0.5 and HCO3 21 +/- 2.0) so that it is insignificant even for the control group. If a concentration exceeding two standard deviations is considered abnormal and a deficit percentage is calculated, it is possible to approximate the total body deficit from the expected values of 50-55 mM/kg and to start proper replacement. In evaluating the results, precise laboratory work must be performed and the clinical condition must be taken into account. Therefore, the method of erythrocyte potassium determination is not suitable for routine work and is used only in case of serum potassium excess values and during prolonged postoperative parenteral treatment.

摘要

由于钾离子在外科病理学及术后恢复过程中非常重要,作者测定了211例患者的红细胞钾含量(对照组37例,病理组174例)。对两组的统计评估结果进行了比较,并研究了血清钾和红细胞钾与酸碱状态的相关性。作者采用了Marongiu改良的方法,用火焰光度计测定红细胞溶血产物中的钾含量。对照组和病理组的平均值分别为84.61(标准差5.24)和85.98(标准差9.10)。血清钾和红细胞钾的相关性受到多种因素影响,仅在有限的pH值和HCO₃区间(pH 7.4±0.5和HCO₃ 21±2.0)内存在,因此即使对对照组来说也不显著。如果将超过两个标准差的浓度视为异常,并计算缺乏百分比,就可以根据50 - 55 mM/kg的预期值估算总体缺乏量,并开始适当的补充。在评估结果时,必须进行精确的实验室工作,并考虑临床状况。因此,红细胞钾测定方法不适用于常规工作,仅在血清钾值过高以及术后长期肠外治疗期间使用。

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