Pietronave Stefano, Iafisco Michele, Locarno Deborah, Rimondini Lia, Maria Prat Maria
Department of Medical Sciences, Università del Piemonte Orientale "A. Avogadro", Novara - Italy.
J Appl Biomater Biomech. 2009 May-Aug;7(2):77-89.
Recent developments in nanotechnology have provided new tools for both cancer imaging and treatment. The functionalization of the nanocarrier based drugs using biological ligands allows increasing specificity of drug targeting enhancing efficacy and reducing side effects. In this paper some current nanocarrier based drugs are described and the principles for their functionalization in cancer treatment and imaging are reviewed.
纳米技术的最新进展为癌症成像和治疗提供了新工具。使用生物配体对基于纳米载体的药物进行功能化，可以提高药物靶向的特异性，增强疗效并减少副作用。本文描述了一些当前基于纳米载体的药物，并综述了它们在癌症治疗和成像中进行功能化的原理。
