Department of Nutrition, Ministry of Health, Muscat, Oman.
East Mediterr Health J. 2010 May;16(5):533-8.
This paper presents the trend of spina bifida and other neural tube defects in Oman after the nationwide implementation of folate supplementation of pregnant women in 1990 and the fortification of wheat flour with iron and folate in 1996. The annual incidence of spina bifida fluctuated from 2.34 to 4.03 per 1000 deliveries between 1991 and 1996, but fell sharply to 2.11 per 1000 deliveries in 1997, after which the downward trend continued, reaching 0.29 per 1000 deliveries by 2006. The rate of other neural tube defects remained almost constant. The reduction in spina bifida rates in Oman could be linked to the start of flour fortification but not the supplementation programme.
本文介绍了 1990 年在阿曼全国范围内实施孕妇叶酸补充以及 1996 年在小麦粉中添加铁和叶酸之后，神经管缺陷（包括脊柱裂）的发病趋势。1991 年至 1996 年，脊柱裂的年发病率在每 1000 例分娩中有 2.34 至 4.03 例波动，但在 1997 年急剧下降至每 1000 例分娩 2.11 例，此后下降趋势持续，到 2006 年降至每 1000 例分娩 0.29 例。其他神经管缺陷的发生率几乎保持不变。阿曼脊柱裂发病率的下降可能与面粉强化的开始有关，但与补充方案无关。
