International Health Division, Department of Epidemiology & Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Vaccine. 2010 Oct 18;28(44):7202-6. doi: 10.1016/j.vaccine.2010.08.056. Epub 2010 Aug 25.
Our objective was to determine age-specific rubella susceptibility among Egyptian females. This was a cross-sectional survey in eight randomly selected communities, with the largest number of reported rubella cases in the 2007 Rubella surveillance. A sample of 5672 females between the ages of 6 and 45 years were interviewed. Of those 602 blood samples were obtained and tested for rubella IgG. The proportion of seronegative females was 9.7%. The highest proportion of susceptible females was in the ages between 6 and 25 years and the highest risk of susceptibility was among unmarried females [odds ratio (OR)=7.2]. The knowledge of interviewed females about rubella, the vaccine and the effect rubella infection on pregnancy and on the fetus was very limited. In conclusion more vaccination coverage is needed, with simultaneous increase of public awareness to minimize the susceptible female population.
我们的目的是确定埃及女性的风疹易感性与年龄的关系。这是一项在 2007 年风疹监测中报告风疹病例最多的八个随机选定社区进行的横断面调查。共采访了 5672 名 6 至 45 岁的女性。其中，采集了 602 份血液样本，检测风疹 IgG。血清阴性女性的比例为 9.7%。风疹易感女性比例最高的年龄段在 6 至 25 岁之间，未婚女性的易感风险最高（比值比[OR]=7.2）。被访女性对风疹、疫苗以及风疹感染对妊娠和胎儿的影响知之甚少。总之，需要进一步提高疫苗接种覆盖率，并同时提高公众意识，以减少易感女性人群。
