达托霉素成功治疗耐甲氧西林敏感金黄色葡萄球菌引起的人工瓣膜心内膜炎难治性病例。

Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus.

机构信息

Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong.

出版信息

Heart Lung. 2011 Mar-Apr;40(2):172-6. doi: 10.1016/j.hrtlng.2010.06.002. Epub 2010 Aug 30.

DOI:10.1016/j.hrtlng.2010.06.002

PMID:20800283

Abstract

We report on an intravenous drug user who presented with methicillin-sensitive Staphylococcus aureus bacteremia and endocarditis of a prosthetic tricuspid valve, with a 4-cm vegetation refractory to standard antibiotic treatment. The patient responded to intravenous daptomycin therapy clinically and microbiologically, despite an absence of surgical intervention.

摘要

我们报告了一例静脉药物使用者，他患有耐甲氧西林金黄色葡萄球菌菌血症和人工三尖瓣心内膜炎，伴有 4 厘米大的生物瓣，对标准抗生素治疗有抗性。尽管没有手术干预，患者对静脉滴注达托霉素治疗在临床和微生物学上均有反应。