Prabhudesai Sumant, Kanjani Amruta, Nambi P Senthur, Gnanasambandam S, Ramachandran Bala
From the *Department of Pediatric Critical Care, †Department of Infectious Disease, and †Department of Pediatric Cardiology, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
Pediatr Infect Dis J. 2016 May;35(5):517-8. doi: 10.1097/INF.0000000000000958.
We report the successful use of daptomycin in a child with methicillin-resistant Staphylococcus aureus endocarditis with persistent bacteremia and clinical deterioration, despite treatment with vancomycin and rifampicin. She had acute kidney injury, requiring daptomycin dosage adjustment.
我们报告了达托霉素在一名患有耐甲氧西林金黄色葡萄球菌心内膜炎且伴有持续性菌血症和临床病情恶化的儿童中的成功应用,尽管该患儿已接受万古霉素和利福平治疗。她患有急性肾损伤,需要调整达托霉素的剂量。