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[在急性失血情况下,使用维生素和代谢物复合物纠正肝切除术中全身和器官血流动力学紊乱]

[The use of a vitamin and metabolite complex for correcting the disorders in systemic and organ hemodynamics during liver resection under conditions of acute blood loss].

作者信息

Shcherban' A N, Korkhov S I, Nazarov N V, Krivitskiĭ N M, Kislukhin V V, Kopytov S V, Kholodov I G

出版信息

Patol Fiziol Eksp Ter. 1990 Jul-Aug(4):28-9.

PMID:2080080
Abstract

The efficacy of some infusion media, vitamins, and metabolites in resection of the liver in acute blood loss was studied in experiments on dogs. Inclusion of vitamins B1, B2, and B6, lipoic acid, calcium pantothenate, nicotinamide, solution of alpha-glutamate and gamma-aminobutyric acid (aminalone) in the infusion led to a sharp increase of myocardial contractility, increase of cardiac output and total hepatic blood flow, normalization of biochemical blood values, and restoration of the activity of hepatocyte enzymes.

摘要

在犬类实验中研究了某些输液介质、维生素和代谢产物在急性失血肝脏切除术中的功效。在输液中加入维生素B1、B2、B6、硫辛酸、泛酸钙、烟酰胺、α-谷氨酸溶液和γ-氨基丁酸(氨基酮戊酸),可使心肌收缩力急剧增加、心输出量和肝脏总血流量增加、血液生化值恢复正常,并使肝细胞酶活性恢复。

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