Giampalmo A, Badini A, Carli F, Castellaneta A, Paladino B, Quaglia A C
Istituto di anatomia patologica dell'Università di Genova.
Pathologica. 1990 Sep-Oct;82(1081):527-30.
More than 50% of AIDS patients show adrenal compromise. The major pathological findings include inflammatory changes of both the cortical and medullary portion with necrosis and haemorrhage. The principal determinant of these abnormalities appears to be CMV infection. We also report the occurrence of focal or subtotal hypophyseal necrosis in the setting of AIDS. These alterations of endocrine glands may deserve attention in the management of the patients.
超过50%的艾滋病患者出现肾上腺功能损害。主要病理表现包括皮质和髓质部分的炎症改变伴坏死和出血。这些异常的主要决定因素似乎是巨细胞病毒感染。我们还报告了艾滋病患者中局灶性或部分垂体坏死的发生情况。内分泌腺的这些改变在患者的管理中可能值得关注。