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[长期波兰-莫妮卡-华沙项目:人群血压模式及选定因素对血压水平的影响]

[Long-term Pol-MONICA-Warsaw project: pattern of blood pressure among the population and the effects of selected factors on the blood pressure level].

作者信息

Broda G, Rywik S, Polakowska M, Kupść W

机构信息

Zakład Epidemiologii i Prewencji Chorób Układu Krazenia Instytutu Kardiologii w Warszawie.

出版信息

Pol Arch Med Wewn. 1990 Oct;84(4):253-63.

PMID:2080115
Abstract

Out of 1800 men and 1800 women being the random sample of population of two Warsaw districts aged 35-64 years, 1309 men and 1337 women (response rate 72.7% and 74.3% were screened in 1984 within the framework of the Pol-MONICA Warsaw Project. Standardized mean values of systolic blood pressure did not differ between men and women but the mean values of diastolic blood pressure were higher in men. Mean values of systolic and diastolic blood pressure increased in both sexes with age, however diastolic blood pressure increased only up to age 45-54 years. Prevalence of hypertension according to WHO criteria was higher in men than in women and in both sexes increased with age. Among subjects with hypertension the mild diastolic hypertension was most frequent. The high percentage of subjects with hypertension at screening was not previously detected (47.4% men and 27.6% women). The fact of hypertension detection was not equal with undertaking therapy because 58.9% men and 46.6% women with detected hypertension were never treated. The effectiveness of therapy (achieving goal) was 24% in men and 27.4% in women. The performed multiple regression analysis indicated that Quetelet index and pulse rate were independently related with systolic blood pressure in both sexes and additionally education level, alcohol consumption and HDL-cholesterol concentration in men and age and family history of hypertension in women. As far as the diastolic blood pressure is concerned the Quetelet index, pulse rate and family history were significantly related in both sexes and additionally in men ethanol consumption and HDL-cholesterol concentration.

摘要

在华沙两个区年龄在35至64岁的人群随机样本中选取的1800名男性和1800名女性中,1309名男性和1337名女性(应答率分别为72.7%和74.3%)于1984年在“波兰-莫妮卡华沙项目”框架内接受了筛查。收缩压的标准化均值在男性和女性之间没有差异,但男性的舒张压均值更高。收缩压和舒张压的均值在两性中均随年龄增长而升高,然而舒张压仅在45至54岁之前升高。根据世界卫生组织标准,高血压患病率男性高于女性,且在两性中均随年龄增长而升高。在高血压患者中,轻度舒张期高血压最为常见。筛查时高血压患者中很大比例之前未被检测到(男性为47.4%,女性为27.6%)。高血压的检测事实并不等同于接受治疗,因为检测出高血压的男性中有58.9%、女性中有46.6%从未接受过治疗。治疗效果(达到目标)男性为24%,女性为27.4%。进行的多元回归分析表明,奎特莱指数和脉搏率在两性中均与收缩压独立相关,此外,男性的教育水平、酒精摄入量和高密度脂蛋白胆固醇浓度以及女性的年龄和高血压家族史也与之相关。就舒张压而言,奎特莱指数、脉搏率和家族史在两性中均显著相关,此外,男性的乙醇摄入量和高密度脂蛋白胆固醇浓度也与之相关。

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