Department of Anatomical Pathology, Royal Women's Hospital, Parkville, Victoria, Australia.
Fertil Steril. 2011 Feb;95(2):803.e3-6. doi: 10.1016/j.fertnstert.2010.07.1068.
To describe the detection of Hodgkin lymphoma within ovarian tissue taken at the time of harvest for cryopreservation.
Case report.
University-affiliated women's hospital.
PATIENT(S): A 19-year-old woman diagnosed with Hodgkin lymphoma.
INTERVENTION(S): Laparoscopic removal of ovarian tissue for cryopreservation.
MAIN OUTCOME MEASURE(S): Histologic and immunohistochemical evaluation of ovarian tissue harvested for fertility preservation.
RESULT(S): Histologic and immunohistochemical identification of Hodgkin lymphoma within ovarian tissue harvested for cryopreservation.
CONCLUSION(S): Ovarian cryopreservation and subsequent autografting is a procedure still in an experimental phase that has yielded promising findings. This option is frequently offered to young women with neoplasms such as Hodgkin lymphoma. Although the risk of Hodgkin lymphoma infiltration into the ovary may be low, the identification of lymphoma in this case emphasizes the importance of histologic examination of ovarian tissue before freezing and indicates that there is a possibility of reintroducing tumor.
描述在冷冻保存时采集的卵巢组织中霍奇金淋巴瘤的检测情况。
病例报告。
大学附属女子医院。
19 岁女性，诊断为霍奇金淋巴瘤。
腹腔镜下切除卵巢组织进行冷冻保存。
为生育保护而采集的卵巢组织的组织学和免疫组织化学评估。
在冷冻保存时采集的卵巢组织中发现霍奇金淋巴瘤的组织学和免疫组织化学鉴定。
卵巢冷冻保存和随后的自体移植仍处于实验阶段，已取得有前景的发现。该选择常提供给患有霍奇金淋巴瘤等肿瘤的年轻女性。尽管霍奇金淋巴瘤浸润卵巢的风险可能较低，但在此例中发现淋巴瘤强调了在冷冻前对卵巢组织进行组织学检查的重要性，并表明存在重新引入肿瘤的可能性。
