Cannon D S, Leeka J K
Psychology Service, Veterans Administration Medical Center, Dallas, TX 75216.
Pharmacol Biochem Behav. 1990 Oct;37(2):379-81. doi: 10.1016/0091-3057(90)90352-i.
Saccharin aversions were conditioned using ethanol (EtOH) in rats of different body weights. There was a nonuniform relation between EtOH dose (g/kg) and strength of conditioned taste aversion. Heavier rats learned stronger aversions at the same dose, and a weak dose (i.e., 1.0 g/kg) was effective only in heavier rats. It is suggested that rats be equated on body weight in studies of EtOH-induced taste aversion learning and in studies of EtOH preference.
在不同体重的大鼠中,使用乙醇(EtOH)诱发糖精厌恶反应。乙醇剂量(克/千克)与条件性味觉厌恶的强度之间存在不一致的关系。体重较重的大鼠在相同剂量下会产生更强的厌恶反应,而低剂量(即1.0克/千克)仅对体重较重的大鼠有效。建议在乙醇诱发味觉厌恶学习研究和乙醇偏好研究中,根据体重对大鼠进行匹配。