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急诊室中的胸痛:HEART评分的多中心验证

Chest pain in the emergency room: a multicenter validation of the HEART Score.

作者信息

Backus Barbra E, Six A Jacob, Kelder Johannes C, Mast Thomas P, van den Akker Frederieke, Mast E Gijis, Monnink Stefan H J, van Tooren Rob M, Doevendans Pieter A F M

机构信息

Department of Cardiology, Universitair Medisch Centrum, Utrecht, Nieuwegein, The Netherlands.

出版信息

Crit Pathw Cardiol. 2010 Sep;9(3):164-9. doi: 10.1097/HPC.0b013e3181ec36d8.

Abstract

OBJECTIVE

Decision-making in chest pain patients is hampered by poor diagnostic power of patient's history, electrocardiogram, age, risk factors, and troponin. Each of these findings may be qualified with 0, 1, or 2 points. Together they compose the HEART score. We tested the hypothesis that the HEART score predicts major adverse cardiac events.

DESIGN

Retrospective multicenter analysis in patients presenting at the cardiology emergency room.

SETTING

Patient inclusion between January 1 and March 31, 2006.

PATIENTS

A total of 2161 patients were admitted, of which 910 patients (42%) presented with chest pain. Analysis was performed in 880 cases (96.7%).

MAIN OUTCOME MEASURES

The primary endpoint was a composite of acute myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft surgery and death, within 6 weeks after presentation, together called major adverse cardiac events.

RESULTS

A total of 158 patients (17.95%) reached the primary endpoint. Ninety-two patients had an acute myocardial infarction (10.45%), 82 a percutaneous coronary intervention (9.32%), 36 a coronary artery bypass graft (4.09%), and 13 died (1.48%). Of 303 patients with HEART score 0 to 3, three (0.99%) had an endpoint. In 413 patients with HEART score 4 to 6, 48 cases (11.6%) reached an endpoint. In case of a HEART score of 7 to 10, an endpoint was reached in 107/164 cases (65.2%).

CONCLUSIONS

The HEART score helps in making accurate diagnostic and therapeutic decisions without the use of radiation or invasive procedures. The HEART score is an easy, quick, and reliable predictor of outcome in chest pain patients and can be used for triage.

摘要

目的

胸痛患者的决策因患者病史、心电图、年龄、危险因素和肌钙蛋白的诊断能力欠佳而受到阻碍。这些检查结果每项可计0、1或2分。它们共同构成HEART评分。我们检验了HEART评分可预测主要不良心脏事件的假设。

设计

对就诊于心脏病急诊室的患者进行回顾性多中心分析。

地点

纳入2006年1月1日至3月31日期间的患者。

患者

共收治2161例患者,其中910例(42%)表现为胸痛。对880例(96.7%)进行了分析。

主要观察指标

主要终点为就诊后6周内急性心肌梗死、经皮冠状动脉介入治疗、冠状动脉旁路移植术和死亡的复合事件,统称为主要不良心脏事件。

结果

共有158例患者(17.95%)达到主要终点。92例发生急性心肌梗死(10.45%),82例行经皮冠状动脉介入治疗(9.32%),36例行冠状动脉旁路移植术(4.09%),13例死亡(1.48%)。在303例HEART评分为0至3分的患者中,3例(0.99%)达到终点。在413例HEART评分为4至6分的患者中,48例(11.6%)达到终点。HEART评分为7至10分的患者中,107/164例(65.2%)达到终点。

结论

HEART评分有助于在不使用放射或侵入性检查的情况下做出准确的诊断和治疗决策。HEART评分是胸痛患者结局的一种简单、快速且可靠的预测指标,可用于分诊。

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