[Effects of medium-term treatment of acebutolol on lipid profile].

The effects of a 12-week treatment with acebutolol on serum lipids have been studied in 18 patients. Acebutolol was given as a 400-, 600-, or 800-mg single daily dose in the morning. Standing and supine blood pressure diminished significantly, whereas the major indexes of lipid metabolism such as total serum cholesterol, HDL-cholesterol, triglycerides, and plasma lipoproteins were not significantly affected. The treatment was well tolerated.