Department of Urology, University of Munich, Munich, Germany.
Eur Radiol. 2011 Feb;21(2):378-84. doi: 10.1007/s00330-010-1935-z. Epub 2010 Aug 30.
Excretory-phase CT urography (CTU) may replace excretory urography in patients without urinary tumors. However, radiation exposure is a concern. We retrospectively compared upper urinary tract (UUT) delineation in low-dose and standard CTU.
CTU (1-2 phases, 120 KV, 4 × 2.5 mm, pitch 0.875, i.v. non-ionic contrast media, iodine 36 g) was obtained with standard (14 patients, n = 27 UUTs, average 175.6 mAs/slice, average delay 16.8 min) or low-dose (26 patients, n = 86 UUTs, 29 mAs/slice, average delay 19.6 min) protocols. UUT was segmented into intrarenal collecting system (IRCS), upper, middle, and lower ureter (UU,MU,LU). Two independent readers (R1,R2) graded UUT segments as 1-not delineated, 2-partially delineated, 3-completely delineated (noisy margins), 4-completely delineated (clear margins). Chi-square statistics were calculated for partial versus complete delineation and complete delineation (clear margins), respectively.
Complete delineation of UUT was similar in standard and low-dose CTU (R1, p > 0.15; R2, p > 0.2). IRCS, UU, and MU clearly delineated similarly often in standard and low-dose CTU (R1, p > 0.25; R2, p > 0.1). LU clearly delineated more often in standard protocols (R1, 18/6 standard, 38/31 low-dose, p > 0.1; R2 18/6 standard, 21/48 low-dose, p < 0.05).
Low-dose CTU sufficiently delineated course of UUT and may locate obstruction/dilation, but appears unlikely to find intraluminal LU lesions.
排泄期 CT 尿路造影(CTU)可替代无尿路肿瘤患者的排泄性尿路造影。然而,辐射暴露是一个关注点。我们回顾性比较了低剂量和标准 CTU 对上尿路(UUT)的描绘。
采用标准(14 例患者,27 个 UUT,平均 175.6 mAs/slice,平均延迟 16.8 分钟)或低剂量(26 例患者,86 个 UUT,29 mAs/slice,平均延迟 19.6 分钟)方案获得 CTU(1-2 期,120KV,4×2.5mm,螺距 0.875,静脉内非离子型造影剂,碘 36g)。UUT 被分割为肾内收集系统(IRCS)、上、中、下输尿管(UU、MU、LU)。两位独立的读者(R1、R2)将 UUT 段评为 1-未描绘,2-部分描绘,3-完全描绘(有噪声的边缘),4-完全描绘(清晰的边缘)。分别计算了部分和完全描绘以及完全描绘(清晰边缘)的卡方统计。
标准和低剂量 CTU 中 UUT 的完全描绘相似(R1,p>0.15;R2,p>0.2)。IRCS、UU 和 MU 在标准和低剂量 CTU 中同样经常清晰描绘(R1,p>0.25;R2,p>0.1)。LU 在标准方案中更常清晰描绘(R1,18/6 标准,38/31 低剂量,p>0.1;R2,18/6 标准,21/48 低剂量,p<0.05)。
低剂量 CTU 足以描绘 UUT 的过程并可能定位梗阻/扩张,但似乎不太可能发现管腔内 LU 病变。